Randomised Double-blind Active vs. Placebo Clinical Trial on the Effect of the Food Effect of the Food Supplement Enterokind® Junior on Irritable Bowel Syndrome (IBS) in Children

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to test a food supplement in children of 3-17 years with IBS. The main questions it aims to answer are: * Is the tested supplement able to improve and/or reduce IBS-related symptoms? * After administration of the food supplement, how does the state of intestinal inflammation improve? * Is the gut microbiota modified? Participants will take the food supplement every day for 2 months. After 30 days and after 60 days, they will be visited from the gastroenterologist. * They have to fill in the questionnaire and the symptom's diary weekly and deliver it to the gastroenterologist during the visits * At the first visit, they will collect the faecal sample for the analysis of inflammatory markers and gut microbiota * After 30 days, they will collect the faecal sample for the analysis of inflammatory markers * After 60 days, they will collect the faecal sample for the analysis of gut microbiota Researchers will compare with placebo to see if the product is effective.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Maximum Age: 17
Healthy Volunteers: t
View:

• Subjects presenting symptoms of IBS according to Rome IV criteria.

• Presence of functional disorders according to assessment questionnaire with a score of 2 or more.

• Age between 3 and 17 years and 11 months.

• Willingness of the subject/parent to participate in the study.

• Willingness of the subject/parent to complete the questionnaire.

• Willingness of subject/parent to use only the product to be tested during the duration of the study.

• Willingness of the subject/parent not to use similar products during the duration of the study.

• Parent's signature of informed consent.

Locations
Other Locations
Italy
Gioacchino Calapai
RECRUITING
Messina
Contact Information
Primary
Claudio Romano, Associate Professor
claudio.romano@unime.it
+39 090 2213818
Time Frame
Start Date: 2023-04-01
Estimated Completion Date: 2025-04-01
Participants
Target number of participants: 128
Treatments
Experimental: Verum
Partecipants received a food supplement with probiotics, chamomile, vitamin A, vitamin D in single-dose vials every day for 60 days.
Placebo_comparator: Placebo
Placebo does not contain any active ingredients. Partecipants received placebo in single-dose vials every day for 60 days.
Related Therapeutic Areas
Sponsors
Leads: Azienda Ospedaliera Universitaria Policlinico G. Martino

This content was sourced from clinicaltrials.gov